Endocrine Abstracts

Context: Recent guidelines recommend a diagnosis of adrenal insufficiency when stimulated peak cortisol level falls below 500 nmol/l. This may not be valid when using a highly specific cortisol immunoassay or cortisol measured by liquid chromatography-mass spectroscopy.Objective: Determine the diagnostic threshold for adrenal insufficiency using a highly specific cortisol assay.Design: For 4 months, all subjects having a dynamic te...